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Bee Hypro D+

Product Name: BEE-HYPRO D+

Drug Category: Synbiotic

Drug form: Water-soluble powder

Target animal: Bee

Enterococcus faecium

Pediococcus acidilactici

Lactobacillus acidophilus

Lactobacillus casei

Bifidobacterium bifidum

Bacillus Subtilis

Prebiotic (DOS)

Total Count > 1×1012 CFU/Kg

Mix 10 grams of the product in a solution of sugar and water (1:3) or add 10 grams of the product in feed of each of hive and place it inside or outside the hive or hang it using WAX paper on top of hive frames.

Mode of action of probiotics

The health and improvement of bee production is dependent on three major factors of genetics, microbiota and stress. The amount of microbiota diversity in the honeybee system includes proteobacteria, alpha-proteobacteria, beta-proteobacteria, and gamma-proteobacteria. Lactobacillus species are less common in the gastrointestinal tract, given that these bacteria are more alien than the aforementioned groups for the bee colony, they can produce a relatively strong reaction in the honeybee. The immune system of the bee is dependent on the antimicrobial peptides, such as Defensins and Abaecin, and the use of probiotics increases the gene expression of the antimicrobial peptides and thus increases the immune response in the honeybee. Bacillus subtilis in this product with the ability to produce antimicrobial and bio surfactant compounds inhibits pathogens and strengthens the antiviral effects. Considering that, the amount and number of carbohydrate and protein digestive enzymes in the honeybee are limited. Bacillus subtilis increases the expression of the gene encoding the peptidase and glycoside hydrolase, as well as other probiotic microorganisms play an important role in the digestion and absorption of carbohydrates and proteins.

Mode of action of prebiotic:

Prebiotics in the BEE-HYPRO D+ is dextran oligosaccharide. The prebiotic is a bacterial exopolysaccharide produced by Leuconostoc mesenteroides in sucrose-based medium. Dextran is resistant to gastric enzymes and in the digestive system, only bacteria that have a dextranase enzyme, such as bacteria that produce lactic acid (As the bacteria present in this product) are able to use it. In this way, the prebiotic in this compound helps to grow and colonize probiotic microorganisms and prevent the growth of pathogen microorganisms. Dextran in the formulation and short chain fatty acids produced by bacteria stimulate the immune system.

Increased the hive population

Increased spawning by the queen bee

Increased honey harvesting

Reduced bee casualties

Increased resistance to varroa destructor

Reduced sucrose concentration in honey

Improve quality of honey

1 kg Plastic Can.

1-liter liquid bottle.

Keep in a cool, dry place, away from exposure to direct sunlight.

Keep out of reach of children.

2 years after production date for powder formulation.

1 year after production date for liquid formulation.

Get in Touch


No. 142/41 West 8th St. Goldasht. Karaj-IRAN

Zip Code: 31979-59658

P.O.BOX: 31995-133 Kamalshahr-Karaj

Phone: +98(26)34806666-7

Fax: +98(26)34804564


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